174: Do Skin Probiotics Work?

Transcript of Episode 174: Do Skin Probiotics Work?

With Dr. Daniel Pompa, Meredith Dykstra and Dr. Shayne Morris

Meredith:
Hello, everyone, and welcome to Cellular Healing TV. I’m your host, Meredith Dykstra, and this is Episode 174. We have our resident cellular healing specialist, Dr. Dan Pompa, on the line, and today we welcome special guest, Dr. Shayne Morris. We have a very interesting topic for you all today, and it is the skin microbiome. Dr. Shayne is no stranger to Cellular Healing TV, but if you haven’t caught him on the show before, let me tell you a little bit about Dr. Shayne. Dr. Shayne is one of America’s leading molecular biologists and herbalomic experts, and his work centers on the body’s epigenetic response to herbal nutrition. His leadership and the clinical results of the supplementation products he has pioneered has earned Systemic Formulas a global reputation as the world leader in cellular healing. Welcome back to Cellular Healing TV, Dr. Shayne, great to see you.

Dr. Shayne:
Thanks. Yeah. That’s amazing.

Dr. Pompa:
Yeah. No. It’s been a while, and I mean, you’re no doubt our favorite biochemist. We had to bring you on because of a breakthrough product. Look, every show we do about the skin ends up to be some of our number one shows so no doubt this one. You guys are going to hear about an amazing product that Dr. Shayne actually developed.

I have to say we’ve heard a lot about the microbiome of the gut, even the oral microbiome. I mean, we hear a lot about how bacteria affect our immune system, how bacteria are responsible for even how our brain works, I mean, all these things, but now, lately, there’s more talk about the skin microbiome. You’ve developed a breakthrough product that we’re going to talk about, which, by the way, is like no other product on the market. We’ve tested them all. This was the only one with actual bacteria that we tested. Meredith, you were in some of that testing, giving Dr. Shayne products that you were using for your skin that didn’t test out. We couldn’t find bacteria in it.

Dr. Shayne, talk a little bit about the skin microbiome. Why is it important? What is it? Let’s start there, go from there.

Dr. Shayne:
Yeah. It is an amazing topic, and you’re right. We focus so much on the GI tract because its relationship to our overall health, right, the gut-brain connection, the gut related to all these inflammatory diseases, which, of course, then are related to autoimmune. Now, the amazing piece here is that, once we have the technologies to start looking at these microbiota, we then ask ourselves where else does a microbiota live? Of course, you mentioned there’s the mouth, and then there’s the urogenital for women. The last frontier became the skin. Why? The skin is the most diverse area we have.

The gut has the same temperature, same moisture. It’s always dark. There’s no oxygen, so we know the kind of environment it is. It’s pretty much the same from top to bottom for the most part. There’s little variations in the mouth and the anus, but it’s much more easily to replicate. The skin, on the other hand, you’ve got oily zones. You’ve got dry zones. You’ve got hot zones. You’ve got cold zones. You’ve got all these global, what do we call them, ecosystems, right?

Dr. Pompa:
It’s like the earth, right?

Dr. Shayne:
It’s just like the earth.

Dr. Pompa:
I mean, you got your cold zones. You got your really humid zones. You got your arid zones, right?

Dr. Shayne:
That’s right. It’s just like the earth, and because of that, there’s a lot of diversity, a huge amount of diversity. We said, okay, we know that, from a detox standpoint, the skin is one of our detox pathways. Wow! We need to consider the skin. The skin is the first barrier to entry for a lot of pathogens. Okay. There’s another reason to study the skin.

Finally, the skin is probably the second to third most abundant immunological site in our body, right? The gut is the first, being the GALT, but the skin is right up there second. It’s our largest organ of our body, so why do we ignore the skin? Not only to mention that, it’s what we look at every day. It’s what we see and feel. It’s all of our senses. Everything that contacts the world around us is through our skin, our eyes. Our skin is the way that we touch the world. It’s amazingly influenced by the microbiota.

We looked at that and said how can we study? -inaudible-, Dan, when you and I started studying microbiota what now, eight years ago, right?

Dr. Pompa:
Yeah.

Dr. Shayne:
The skin -inaudible- we didn’t have the tools. Now that we have the tools, we started down the road of what do we do about the skin microbiota? How do we address the health of skin microbiota? Up until recently, it was through the gut because there is a gut-skin connection. When you have a healthy gut, you have healthy skin, for the most part. There’s some healthy people—or healthy guts have healthier skin. Okay. We now know there’s a skin-gut connection. How do we address the skin inward to the gut and the gut outward to the skin? We’re getting better.

Dr. Pompa:
On some of my research on this, I was shocked, actually, to find that the skin microbiota affects the gut. I’m back and forth. Meaning that they learn through some studies that, oh, my goodness, this microbiota actually can affect the gut. Like I said, to my surprise, I never would’ve thought that would’ve been true, and I was shocked even. This really applies to people’s health. If you’ve had trouble fixing your gut, listen to this show. Obviously, if you’re concerned about your skin in any way, whether it’s eczema, colitis, and you should hear some of the testimonies that I’ve had with just this odd skin condition, listen to this show.

I mean, my point is it affects more than just the outward appearance. I know, some of you who’ve been watching this, that’s what you’re concerned with. It really does go deeper than that. This is more than just skin deep.

Dr. Shayne:
It really is more than skin deep. On that note, let’s make a new triad. We know of all the triads in the body, right? There’s the liver-adrenal-pituitary axis and stuff. Now let’s look at the new triad related to microbiota, and that triad is the skin-gut-brain axis, right? We now know the brain-gut axis and the gut-brain access, right? That is a reversible axes. You just mentioned the skin-gut, the gut-skin axes. On your show, I think we should propose there’s a skin-brain, brain-skin axes, so all three of those make a new triad for us to try to understand.

Anecdotally, it’s true. When you think about when you’re emotionally wrecked, your skin becomes wrecked. Your gut becomes wrecked. When your skin is wrecked, you’re emotionally wrecked. You’re mentally wrecked. You’re psychologically wrecked. Your dopamine’s changed. Although, I think we’re the first people proposing it today, I do believe it exists. I believe that the brain and the skin are intimately related, and we know using this product and using other research that we’re affecting things in people.

You talk to any teenager with acne, and tell me they’re not depressed, right? Tell me that they’re not psychologically impacted. Sometimes their neurotransmitters are of an all-time low, and it’s because of their skin, when you think about it, right? Then their gut’s a wreck. We know for many, many—again, many anecdotal, I think that’s a real pursuable—and it’s something we want to deal with. This product was one of those ways to do that.

We come at things, Dr. Pompa and I—I think you and I come at things from a really—people that are in a really bad place. This could also be people that are in an okay place, and they can benefit from it. You can be healthy and benefit from it, right?

Dr. Pompa:
Yeah, absolutely.

Dr. Shayne:
You don’t have to be a wreck to benefit from this work we’re doing. You can be—I use it every day. I’m not a wreck per se, but I use it. I’ve used it on infants now. At your Atlanta show, we had—I had at least two dozen testimonials come up to me at your Atlanta show showing me pictures of how it’s changed people, how the skin microbiome product, Skin Colonizer, changed people. It was amazing to hear. It was an amazing experience. Before we talk about the products, I’ll let you chime in a little.

Dr. Pompa:
You know what? I just had a client yesterday that literally said—we were going through her products. I said, “Oh, how is the Skin Colonizer working for you?” “Oh my gosh, I love that product.” I’ve seen it work on stretch marks. I’ve seen it work on the psoriasis. I’ve seen it work on just the impossible area of skin, which they’re not sure what’s going on. I could go down the list, and I have some autoimmune skin issues that it’s made a dramatic difference on.

One of the things that I—when we first showed this product or debuted the product, whatever, it was at a seminar here in Utah. I did a lecture about how to apply it after a far infrared sauna. Literally, in the far infrared sauna, you’re opening up those skin pores. You’re making the soil, basically, ripe to put this on. Now, you can put it on anytime. I mean, after a hot shower is when I typically put it on because it’s easy, but after a far infrared sauna, some of these really hard skin cases is when I have them apply it. The results have been absolutely spectacular.

There’s something that happens when you go from hot to cold. This change in the microbiome starts to occur, so applying it right then, I think there’s some magic in that. I talked about that in my lecture, so no doubt we’re going to get the question of when to apply it. I think after you’re cleaning your skin is a great time, and especially if you want even more of a reaction, do it after you do a far infrared sauna. Hit the cold shower. Make that temperature change. Challenge the microbiota, and then add the Skin Colonizer after.

You don’t’ even have to do the cold shower if you’re not one of those. That’s me. I do that. I try to create that adaptation and get that microbiota to change. Anyways, so we’re going to get that question. That’s answered.

Let’s talk about the product a little bit. We tested. You tested. We sent you some products that—and I don’t want to name names, but they were the leading products out there as far as boasting about—and believe me. They are the leading products because Meredith found them. They were boasting about their bacteria in their product and how it was amazing for the skin. We brought it to the lab. We tested all of these products, and I think you found some other ones. You couldn’t find any living bacteria in the product. Is that correct?

Dr. Shayne:
Yeah. I think, in the end, I tested somewhere in the neighborhood of 20 different products.

Dr. Pompa:
Wow.

Dr. Shayne:
At the end, it was. You’re right. We looked at it, and said, okay, what’s going on with these products? Why can they claim that? I started to really dissect the labels as well. In many cases, you can see the title of the product is probiotic cream, but when you start dissecting the label or looking at what they do, go to their website—I went to every website. You see that what they did in many cases was they take a probiotic like something you buy over the counter, a Lactobacillus or a Bifidobacterium. They grew it in a—let’s say a liter. They killed it, and they used that ferment as an ingredient.

It’s not the worst case scenario. Some of these products were using dead bacterial components as part of their product. However, that’s not the ideal scenario either, is it? There are some attributes to the metabolites of bacteria. No doubt. We’ve studied those for years, but it’s somewhat deceiving when it reads probiotic. It took me months to figure all this out, and you’re right. None of them was alive.

Now, I also found something about regulatory that tipped the scales. In the cosmetic industry, you can’t have live organisms, so this is a dietary supplement that you can apply topically. The cosmetic world can’t legally have live organisms. There’s some exceptions in Europe, and so I bought the European products. The European products that I had shipped over here were on their last leg. About a week of shipping killed them.

Then I asked myself—okay. I’ve been spending years on this project, and I can tell you from that experience it’s really hard to keep probiotics alive out of their element. When they’re not happy, they’re not alive. It took me years. I studied these creams. We tested. We tried all sorts of iterations ourselves, and these guys would die.

Then I said, well, what is it that the body—how does the body keep these guys alive? They’re on the skin, and the skin’s a horribly harsh environment. It’s exposed to everything. How is it that they’re living? Your body produces these hydrolipid or sebaceous fluids. Those fluids become the key here. The bacteria love and can live in these oily, water-oil sebaceous hydrolipid layers, right?

What we did is I looked at all the oils or all the breakdown of a sebaceous fluid or a hydrolipid fluid, all the fatty acid content. Amazingly, Dr. Pompa, it’s an omega-6, a little bit omega-3, and [waxen], right? There’s this beautiful ratio again of mostly omega-6s. There’s some fatty acids. There’s some waxen. We rebuilt that same profile using -inaudible- in vegetable or plant-based oils. It’s in the formula. They survived. The bugs survived in the oil, and that was the key.

Dr. Pompa:
How long have you been testing these products? I mean, we’ve had them now for a while. You’ve been testing some of the ones just sitting out. How are those tests coming up? Meaning how are the bugs living now?

Dr. Shayne:
Yeah. The bugs, what, they’re over six months old, still doing fine. Some are more sensitive than others, and so what you’ll find if you were to test my products is you’ll find that my label claim is below what’s actually there because I’m accounting for some death, some die off. When you first buy the product, it’s going to be way higher than the actual label claim of a billion because I need to allow for some dying as well. Some are more sensitive. Some of the Bifidobacterium, I have to add more of them.

Now, the fun thing about is formulation, so we have the hydrolipid-based formula. Let’s look at the probiotics. There’s two categorical ways to think of the probiotics. There’s the Lactobacillus, [Bifidobactus]—Bifidobacterium, excuse me, the Lactococcus, and the Bacillus species. Those are all species that are known to positively benefit. A lot of them are soil bacteria.

They benefit your skin, but they don’t live on your skin. They’re transient. They do what your sauna does. They shake things up. They produce the antimicrobials. They help get rid of pathogens. They’re transient, but they produce a lot of really fun things while they’re on your skin.

The second category is the staph xylosus and staph epidermidis. Those are commensals. Those get on your skin at any age, and they start to train your immune system to behave. They’re the ones that stay there, and they outcompete staph aureus. They outcompete Streptococcus. They outcompete Pseudomonas, and they outcompete Propionibacterium acnes. They become these really amazing guys to stick around because they get rid of the guys that are dangerous.

Dr. Pompa:
Yeah. How we’re seeing an improvement in these autoimmune skin conditions, which, by the way, are so numerous, it’s probably those guys that are having the greatest impact, right? If your body’s own immune system is attacking certain bacteria, other bad guys then can start to overtake, and these guys cause that balance in between.

Dr. Shayne:
That’s right. That’s exactly right. These guys will stick around, and they’re the tougher ones too. When they’re in this formula, they don’t die because they’re used to that sebaceous oil, and then when they go on your skin, they can take up residency because they want to be on your skin. All the studies point down this path, even the ones that I haven’t done, buy all the university studies show that the healthy staph epi and the healthy staph xylosus—for T reg maturation, right, to help your T cells, your T-lymphocytes to mature and behave properly so they don’t create an immune response. They also help outcompete those other guys. Then your skin isn’t losing the tight junctions.

We talked about that triad. When you think about the skin, I want everybody listening to think. Okay. We have brain-gut-skin. I want you to think of the skin tissue as so incredibly similar to the GI tract or the blood-brain barrier. There are tight junctions. There’s the immune system present. There’s the neurological system present. All these systems have to be happy.

One of the ways to do that is maintain a healthy tight junction. If you do not maintain a healthy tight junction, the immune system goes awry. We start inflammation. We even start autoimmune. Guess what? These commensals like staph aureus and staph xylosus help keep that tight junction happy.

Dr. Pompa:
Let me bring that into perspective for people what we’re talking about. Not everyone. Most of our listeners have heard about leaky gut, and that’s basically a compromise of your tight junction. These barriers in your gut that keep the stuff your digesting in the gut not going into your bloodstream and your immune system, creating inflammation. Ultimately, making you feel bad. Nobody wants leaky gut. It leads to autoimmune and other problems. Then we have the blood-brain barrier, which is a protective barrier, so stuff doesn’t get into your brain, toxins, etc., bad guys, bacteria pathogens, very, very important. Then we have a tight junction that you’re saying in the skin that protects, obviously, our immune system, etc.

Some of the stuff that I had read talked about this important communication between bacteria from your skin, to your gut, to your blood-brain barrier, and I’m sure other tight junctions, right? The point is is these bacteria are communicating, and that’s why, when you affect the skin microbiota, you’re affecting the gut. You’re affecting the brain or vice versa, right? This is an important communication network that we don’t even really understand. We just know it exists. Am I correct on this?

Dr. Shayne:
That’s exactly right. We’re just barely scratching the surface on this. We understand the gut a little bit better than anything else, but we’re now seeing the connection between the gut and the skin. There is communication. Some of the organisms that we eat affect the skin immediately, right, immediately. There’s a communication that happens just like a pinprick, right? There’s this amazing intense way that our body is communicating with not only the microbiota but with itself into the brain.

Again, we’ve got this new triad, the gut-brain-skin axis. I think this is an amazing triad that we—that helps us understand what’s happening during detox. The skin is one element of that. We know it gets affected. Meredith mentioned something earlier before we got on about her skin responding to a detox. People on the packages, all of the Prep, brain, body, these detoxing reactions some people are having are related to both the gut, the brain, and the skin, and now, we have an additional tool.

One of Dr. Pompa’s responsibilities at the next Sunshine is to take us to the next level, right? There’s so many people getting involved in the first level of detox, but there’s more levels. There’s going to be more layers of this. As toxic as our world is, this isn’t going to end. This is not a story that’s going to go away. This story is going to continue to become a book, become a movie, whatever you think of in analogies, and the skin is now an integral part of this. We have a sleeping giant here. Nobody else, like you mentioned, has the ability to address the skin microbiota like we do now. There’s nothing else on the market that can address skin microbiota in this fashion.

Dr. Pompa:
Yeah. No doubt about it. Meredith, if you could show the product, actually, it would be great. You could see that. Yeah. There it is.

Meredith:
Yeah, an oil. Mm-hmm.

Dr. Pompa:
By the way, when we say bugs, we’re talking bacteria. Shayne and I say bugs, and people are like, what? I don’t want bugs on my skin. Yeah. I mean, it is remarkable.

One of the studies that I actually showed was they took mice. These were mice who were not able to lose weight, weight loss resistant. Obviously, a gene was triggered, etc. They took the mice from a hot environment to a cold environment, like infrared sauna to the hot-cold shower. After doing that a few times, they realized the mice were then able. It kicked in weight loss. In the study, it talked about they believe it was the change in the microbiota, the microbiome that actually triggered the change.

Now, one of the theories was is that it actually was the microbiome here on the skin that actually responded to the cold temperature, sent, obviously, signals to the gut microbiome, had an effect on the hormones, which had an effect on the weight loss. There’s just an example of they didn’t know exactly what was going on, but they measured the microbiome. They saw the change, and it was due to the temperature, the regulation. We know that this communication exists.

Dr. Shayne:
I think that group might’ve taken it a step further. Yesterday, a publication came out from a group where they’ve now linked that change to insulin resistance. When they change the microbiota, the insulin resistance went away. When they gave it bad microbiota, the insulin resistance kicked back up, so now you have skin microbiota relating some way, shape, or form to insulin resistance. They’re going to be…

Dr. Pompa:
It will cause weight gain, which will cause weight gain loss, exactly. Send me that study, man. Come on. Send me that. We got to share that. I need that.

Dr. Shayne:
Yeah. No kidding. Yeah. I get so busy I forget to perpetuate the crazy stuff that’s going on.

Dr. Pompa:
You got to spread the knowledge. I put that on top of my knowledge base, and you put stuff on your knowledge base. Okay. People want to hear, okay, what do I use this for? I talked about how we use it, but you don’t need much either. I guess I didn’t answer that. Just coat the skin. I mean, that’s pretty much it.

Dr. Shayne:
Yeah.

Dr. Pompa:
Yeah. It goes a long way.

Dr. Shayne:
On skin, it has obvious issues where it’s obviously inflamed, whether it be a rash, or a dermatitis, or anything you—any obvious association, put it there. You got to do it two or three times a day. Once a day, doesn’t work. I notice that sometimes that causes it to—it soaks in. It’s an oil, but it doesn’t stay oily because, the waxes, the waxes help trap in the oil and keep the moisture in there too. You do have to apply it multiply times for—the worse the case, the more you apply, I’ve noticed.

Furthermore, we are going to be in the future coming out with the equivalent pill so that we can work inside out, outside in. The similar organisms will be dosing orally, and then you simultaneously work that with the pill. I did a recent study on five people here at work. Their skin conditions improved more rapidly when they were doing inside out, outside in, so to speak. That led me to the concept that we need to go down that path soon, but right now, we’re getting amazing results outside in, which is topically.

Dr. Pompa:
Okay. People are going to ask. Can you take this orally?

Dr. Shayne:
Yeah. You can. It’s a little bit off-putting because it’s oily, but it’s perfectly safe for oral consumption. It’s just different. Yeah.

Dr. Pompa:
Is it good for the oral microbiome? If someone has something gum related, teeth related, is it good for that, or is it -inaudible-?

Dr. Shayne:
That’s a great question. It wouldn’t certainly be harmful, but in terms of the benefit, I don’t know the answer to that.

Dr. Pompa:
Yeah. That’s interesting. You would know better than I how similar this—these gum, I mean, this is tissue very similar to this tissue. Obviously, differences but, still, there might be a very similar microbiota here versus around the gums than it is on the skin. Who knows? Talk about some of the other things. People are going to ask, well, what about wrinkles? I mean, the microbiota affects the collagen, elastin, which is a big part of your aging of the skin, talk about that. We talked about the autoimmune skin, but what about acne too so wrinkles, acne?

Dr. Shayne:
So far, with older a person acting, we tried it on some people that are in their 20’s and 30’s, and it did improve the acne response for sure. What we haven’t still yet tried it on are teenagers that are extremely oily. They’re going through puberty and their skin is changing dramatically. It’s one of the few times in your life where the microbiota changes from a previous to an adult—or excuse me, adult microbiota. I don’t have an answer to that yet. People that have already gone through puberty, it is beneficial for acne as well.

The wrinkles and things, the only thing I’ve gotten feedback there because I haven’t done anything in a more analytical clinical setting is that the hydration went up. As long as they were drinking good water, the new formula allowed the skin to stay more hydrated, which clearly keeps wrinkles at a minimum. They’re still there, but the hydrated skin is a much better looking skin.

Dr. Pompa:
It’s like I said. We can’t make claims because we don’t have that study. Ultimately, knowing how the microbiome of the skin affects collagen, elastin, I mean, the tissues, etc., I mean, obviously, there’s an effect. Before you make the claim, you have to prove it. Scientifically, we can identify it, but there’s more to it than that.

Dr. Shayne:
I do agree with you. I think we’re on to something. I think this is the beginning of what’s going to become a very large body of evidence. I think that we’re just approaching the beginning of what’s going to be good for our skin. I think that, the past, where we thought about skin as being slathering on things and killing, either killing or slathering, was now an outdated concept or will become an outdated concept. I think this new approach to the skin, I think you’re right. I think the tissues that will be exposed to a healthy microbiome are going to produce more collagen. I think they’re going to be more hormonally regulated. I think they’re going to be so many benefits as we move forward. I think it’s just the beginning of this. Yeah.

Dr. Pompa:
Yeah. No. I think you’re right. I think we’re way ahead right now in this area. I mean, I know we’re ahead just in the microbiota, the microbiome. Now we’re pulling in the skin and just learning. I mean, our feedback with skin conditions, autoimmune has been spectacular. We know that there’s something bigger here. Like you said, even for detoxification, what is it doing? We don’t have all the answers yet, but we are definitely on to something here.

Dr. Shayne:
Yeah. We are, and we’re not alone. You guys have all heard about the Human Microbiome Project. There’s a subset of that project that was focused on the skin, and it was being done at UCSD, San Diego. Just recently, that group spun off a company that is looking hard at doing what we’re doing. They are fervently trying to create products that affect the microbiota of the skin. We’re not alone, and there are amazing people in this work. Not only are we not alone, those people that are even -inaudible- what we’re talking about today can be self-assured that the rest of the world is going to come to the same conclusions that we’re talking about today. It’s just going to take more time for them, but we’re definitely on the forefront of what’s some amazing stuff.

Dr. Pompa:
Yeah. No doubt. Meredith, I know you have some questions, and you’ve been using the product.

Meredith:
Yeah. I have, and I’ve been really enjoying it. It’s really helped me. I know I shared with you, Dr. Pompa and Dr. Shayne, before the broadcast. I had had a crazy skin reaction last week. I don’t know. I think it might’ve been synergistic with some of the detox I’ve been doing and things.

Not to scare anybody, but these things come out of our bodies. Our skin is a major detox pathway. I have been using the Skin Colonizer, and that’s been really helpful with after—I woke up last Monday to all of these welts all over my face. It was crazy. Then the bumps are pretty much healed, but now it’s become dry. This has been really helpful for the dryness.

I was thinking too of our concept of variation and how important that is with diet and exercise. I’m wondering too if it would be good to vary this product with some other ways of topically getting bacteria on our skin as well. I know, for example, in the past, I used to do a yogurt face mask, or even dirt or clay, or things like that topically on the skin. What do you think of the variation?

Dr. Shayne:
Yeah. Diversity is key. Not to sound politically correct, but diversity is a great thing. Not only that, we’re looking at a bunch of other products for that reason. Not just this, but we’re looking at some other things to help create the diversity. The two types of probiotics in this product are there for that reason. There is the commensals, and there is the ones that are transient to help create the diversity.

One other study that’s shown recently is that when you add organisms to a tissue, whether it be the gut or the skin, that don’t reside there, they still cause enough change in microbiota that they can actually reverse dysbiosis. Just by the mere fact of their presence being there, shaking things up, they themselves can reverse dysbiosis by being transient. You don’t have to live there to help benefit the skin, so diversity is an amazing thing in my opinion.

Meredith:
Awesome. What are some other ways that we can build a healthy skin microbiome other than just the topicals? I know that obviously has to do a lot with our gut and the inside as well.

Dr. Shayne:
Yeah, diet for sure. I mean, we know that the future products are going to include some botanicals, but the mantra that we’re now telling people when it comes to the skin is inside out, outside in nutrition. We’re trying to partner or push out the concept that you work topically from outside in, but you have to work inside out, which is dietary. The botanicals, the detox packages that we’re talking about, the brain prep, the TCD work that you guys are doing, that in itself I guarantee you changes the skin microbiota as much as it does the GI microbiota. These are all beneficial for long-term health, right? It takes a while, but for long-term health of the entire ecosystem, that’s all good. Inside out, outside in is our new mantra.

Meredith:
Obviously, rotating the fermented foods and being in the dirt. Maybe we want to mention too just all of the antibacterial cleansers on the market and just the culture of fear around bacteria on our skin, but just a reminder that we need it in the right doses. Then even just putting it on our skin might be a new idea to some. I know not a lot of our listeners. It’s so important to remove the idea that we need to get rid of this bacteria and that it’s bad, but we need that healthy balance to have healthy skin and healthy gut and healthy body.

Dr. Shayne:
Yeah. I’ve got a small group of people that are on the Prep, the Body, the Brain. I’m sure you guys know who they are too, but what they called in and told us is they also took BIND. They opened up a bunch of capsules of BIND, and they made BIND facemasks every night.

Dr. Pompa:
Oh, wow.

Dr. Shayne:
Then they would do the skin microbiome following the facemask.

Dr. Pompa:
That’s smart.

Dr. Shayne:
They’re reporting amazing results with that idea, right? I thought, how brilliant. I’d never even thought of that.

Dr. Pompa:
I didn’t think about it.

Dr. Shayne:
Yeah. It was really fun to hear. People are expanding our knowledge just through their own experimentation, and it’s really fun to see this take off. Yeah.

Dr. Pompa:
Yeah. It’s like a clay mask. I mean, you’re pulling—look, we know that, again, one of the benefits of doing it after a far infrared sauna, yeah, it’s the adaptation. However, it also empties those pores, right, of toxins that would actually have a negative effect against those bacteria.

Dr. Shayne:
That’s right.

Dr. Pompa:
Basically, colonizing, if you will, right, so you’re opening up the pore, getting rid of toxins that would kill the bacteria. That’s one of the reasons why far infrared sauna works too, but the mask would do the same thing. The BIND would pull out toxins, open up those pores, get rid of the chemicals, and leave a better—it’s like getting rid of bad weeds, right, or clearing your soil of glyphosate that kills things, right? It’s like now you’ve got this great soil. It’s good. I like that.

Dr. Shayne:
The skin microbiota has the potential to convert toxins into worse toxins, just like our gut does, right?

Dr. Pompa:
Absolutely. We’re talking about this connection, the brain, the skin, the gut. Of course, we know that the detox affects the gut microbiome, right? Utilizing, now thinking of the Skin Colonizer as opening up this other pathway. We know these bacteria are feeding these bacteria. Okay. As we’re thinking about this triad, what are some of the things that you would say would be good for the brain? I always loved the pituitary because it’s so poisoned, right, and NeuroSyn. What are some other things perhaps that affect the blood-brain barrier with those?

Dr. Shayne:
Yeah. That’s a great question. Clearly, I think, when we’re looking at the barriers, it’s a wonderful thing to add to your protocol, the LGUT, right, which is the leaking gut product. LGUT is amazing for the tight junctions.

Dr. Pompa:
Yeah. We add it. Yeah.

Dr. Shayne:
The other piece would be, as you mentioned, the CALM and the NeuroSyn, amazing results with CALM and NeuroSyn. I’ll tell you. Some people in your group have added NeuroSyn to the Brain Phase, and they’re reporting back to Systemic great results there too. I guarantee that is related to this whole gut-brain-skin connection.

Dr. Pompa:
Yeah. No, exactly. We added a lot, NeuroSyn, for that reason. It helps that blood-brain barrier and, obviously, even just the brain in general, which is really what’s poisoned. Gb is another one, the pituitary. It’s such a big game player as far as regenerating the brain so CALM, NeuroSyn, Gb, LGUT, the Skin Colonizer, all really important. Often times we even need to support the thyroid and the adrenals more, so there’s a couple other considerations that I teach on but, yeah, good stuff.

Dr. Shayne:
Yeah, excellent. There is one other secret that we have. That’s the number 1, which is the…

Dr. Pompa:
Hypothalamus.

Dr. Shayne:
Hypothalamus, yeah. Yeah. I mean, you can do a lot with just what we’ve talked about. There’s a lot of tools that can go a long way, right? I mean, we love simplicity, which is what those packages create, but going to the next level, it’s nice to have those additional tools to…

Dr. Pompa:
Yeah. Those are some of the things that we do, for sure. Yeah. No. As we think about using this product, I’m thinking vaginally. What other possible uses?

Dr. Shayne:
So far, I haven’t heard the vaginal part. That’s totally reasonable. It works. It can be used in every orifice, in every part of your body. I’ve used it in my ear. I’ve used it all over my body. Since its launch introduction, we focused on inflamed tissues, right, tissues that we’ve had trouble with, but there have been a group of people, healthy people, that are putting it—using it as a daily moisturizer. The only complaint I’ve had about that is they go through it more quickly than the people using it as a more specific colonizer.

People using it as a daily, they just go through the bottle much more quickly. That’s not a bad thing. I mean, it’s a little more expensive, but it’s an amazing testament that it’s good for all skin types. There’s been very little backlash. There’s been a few people that put it on their skin and had a very, very temporary—less than a 24 hour response to it. Then by the next day they were using it they were thrilled again. That was even very isolated. Out of the thousand people using it, it was maybe two people that have reported any adverse response to it.

Dr. Pompa:
Yeah. That’s awesome.

Dr. Shayne:
You can use it pretty much anywhere. I use it on my scalp. Microbiota, -inaudible- microbiota, they’ll actually outcompete things like fungi. Warren mentioned that it’s helping—on a project he’s working on, it’s helping, and that’s a fungal related issue.

Dr. Pompa:
-inaudible-.

Dr. Shayne:
Yeah. It’s all fungal, and it can help out.

Dr. Pompa:
[Tinea versicolor], right, exactly, I mean, it’s a fungus that basically lives on you forever. I know. It’s like nothing works for that. People use Selsun Blue and different things, but evidently, it’s working on it so, yeah, just another idea.

Dr. Shayne:
Yeah. I’m -inaudible-. I really do hope it works for him. That would be amazing, another amazing piece of information.

Dr. Pompa:
Yeah, absolutely. Listen, we appreciate you coming on, and I think we’re going to have you back soon. In the past shows, we’ve talked about different bacteriophage, and we’ve got something new coming up. We’re talking about affecting the microbiome in the gut, but we’ve got something new coming up. We’re going to have you on shortly again because I think we keep breaking through with some of those areas too, so I’m not going to tip our hat too much.

Dr. Shayne:
Always a pleasure, it’s always fun being on.

Dr. Pompa:
Go ahead, Meredith. I’ll turn it back to you.

Meredith:
All right, thanks, Dr. Pompa. Thank you so much, Dr. Shayne. This is an amazing product. So many people are loving it, and it’s just another amazing tool in our toolbox for cellular healing. Thank you so much. We’ll look for the new product, and we’ll see you soon out in Utah next week, really excited about the seminar. Thanks, everybody for tuning in, and have a great weekend. We’ll talk to you next week. Bye-bye.