Episode 280: Mimicking Calorie Restriction with Oxaleoacetate
with Alan Cash
Today I welcome Alan Cash, a physicist who has studied the energy pathways associated with calorie restriction.
Alan is here to discuss the latest research on optimal cognitive functioning, steps you can take to produce more mitochondrial mass, the benefits of oxaloacetate supplementation, and what you can do to lessen brain damaging inflammation.
More about Alan Cash:
Alan Cash is the founder and CEO Terra Biological LLC. He's a Physicist who has extensively researched the use of oxaloacetate as a calorie restriction mimetic. He's also an Inc 500 company Founder & CEO, Ernst & Young Entrepreneur of the Year Finalist, Deloitte and Touche Technology Fast 50, and awarded Top 100 Hot Firm.
Additional Information:
Use the code benagene5 for $5.00 BenaGene on Revelation Health
Fastonic Cellular Molecular Hydrogen – Support all forms of fasting with molecular H2!
HCF's Live It to Lead It event – Newport Beach – November 14-17, 2019
Transcript:
Dr. Pompa:
Have you ever heard of the word oxaloacetate? I’m sure most of you haven’t, but you need to. This molecule has been stabilized, and it’s a molecule that works in our cells, in the mitochondria. It can transform your cellular function and your health. As a matter of fact, we’re going to talk about some of the clinical trials for Alzheimer’s, for aging, for some other conditions, and I’m telling you, this one compound has transformed many people’s lives. You’re going to hear all about it and why I believe it’s something you should add to your supplement regiment, so stay tuned. I’m interviewing the physicist who discovered how to stabilize this important molecule, oxaloacetate, on this episode of Cell TV.
Ashley:
Hello, everyone. Welcome to Cellular Healing TV. I’m Ashley Smith, and today we welcome Alan Cash, a physicist who has studied the energy pathways associated with calorie restriction. Alan is joining Dr. Pompa today to discuss the latest research on optimal cognitive functioning, steps you can take to produce more mitochondrial mass, the benefits of oxaloacetate supplementation, and what you can do to lessen brain-damaging inflammation. Enjoy the show. Welcome both of you.
Alan:
Thank you.
Dr. Pompa:
Yeah, Alan, I told you before we got on I’ve been waiting for this interview. I couldn’t wait to do it because it’s a subject that I really love and I know a lot about. I’m sure most of my listeners don’t know a lot about it, and actually, in my new book, Beyond Fasting, I talked about oxaloacetate. Beyond Fasting, right, I mean, fasting, we’re able—what you were able to do as the developer of this, I don’t know, I guess call it a molecule that mimics fasting, so oxaloacetate can mimic this. Let’s just start where you think we should start as far as what is important for people to know. Actually, let’s start here. How the heck did you get into this, discovering this oxaloacetate that here on Cell TV is a big deal because this changes our cell function?
Alan:
Yeah, it’s a pretty weird story. I was out sailing with my wife. I came off the boat, and I fell to the ground. I had this just enormous pain. On a scale of zero to ten, it was a solid ten. It was on my knees, and then it was gone. Being a guy, I just ignored it, but then it came back two days later just for a short time. Then it was gone again, and then it came back in one day, and then it came back in 12 hours. It was getting worse and worse.
My wife booked me a variety of doctors by just saying I’ll take the first cancellation. I’ll take the first cancellation, and I ended up seeing ten doctors in nine days. I saw a neurologist. I saw a gastroenterologist. I saw a heart specialist. I saw a family physician. I saw an acupuncturist. Finally, a neurologist thought that it might where a nerve crosses over with an artery. The artery, as your heart beats, it starts cutting through the nerve bundle. They said, well, it’s either that, or you have multiple sclerosis, or a brain tumor.
I had an MRI. They didn’t see anything, and that was the criteria they used to say it might be this artery impinging on a nerve. My wife, again, called up. Where can I find some help for this? There were two places, the University of Pittsburgh, which aren’t you from Pittsburgh?
Dr. Pompa:
Originally, I live in Park City, Utah now, but yes, I originally grew up and born and raised in Pittsburgh.
Alan:
Yeah, it turns out there’s two places in the United States that specializes. Pittsburgh is one of them. The other she called up is two miles away from my house. It’s at UCSD, University of California San Diego. When she called up, the head of neurology answered the phone and said, “Oh, you have what? Oh, well, come in tomorrow morning.”
Dr. Pompa:
That’s not what you want to hear, by the way.
Alan:
It was very surprising, a little scary, so I went in the next day. I showed him my MRIs. At this point in time, I couldn’t even talk. When I talked, it would fire off all my nerves. It was like turning on an electrical appliance in your throat. Imagine Frankenstein with the two bolts coming out and putting a car charger to it. It was just horrible.
He looked at my medical file, and he said, “Okay, let’s—I’ll rearrange the hospital’s operating schedule for tomorrow. Take these drugs. Just get through the night, and we’ll take care of you,” so did that. They did a six-hour brain surgery where they went into the back of my head. They followed the nerve ‘til they found where it crossed over. They pulled it apart, and they put in a piece of Teflon and sewed me back up. I’ve been pain-free for about 12, 13 years now.
Getting to the reason we’re ill, in this case, it was a mechanical problem, and fixing that solves the problem. How often in medicine do we not do that? I mean, do we just look at the symptoms, and try to patch the symptoms? Oh, you’ve got high blood glucose. Here, let’s put a patch over here. If we could find out what’s really wrong and fix it, you get a long-term solution that makes you a lot happier.
I had a lot of things happen to me very favorably as a result of this. As a physicist, I tried to figure out why did this happen? It appears that, in aging, normal aging, our arteries get longer as we age. They have to have somewhere to go, so they just fold over. It’s not a big deal, unless they fold over next to a nerve bundle and start cutting it in two like a little saw. I thought, well, why don’t—as a physicist, why don’t I look at aging? What we do in physics is we take a lot of data, and we try to find that little kernel that makes sense, that describes all the data. When I looked at it in regards to aging, what I saw is not very much changes how we age. One thing that stood out, though, was calorie restriction.
Dr. Pompa:
Yeah, no, by the way, I always say that that’s really the only thing. There are solid studies showing that, if you want to age slower, caloric restriction is about it.
Alan:
That’s all I could find. When I was looking at this, there was a lot of work going on at MIT and Harvard looking at some of the mechanisms of calorie restriction, particularly increasing NAD+ levels and decreasing the NADH levels, which they’re a currency to switch electrons back and forth so NAD+ and NADH. Changing that ratio seemed to be the way to affect calorie restriction, to get the ball rolling, to get the molecular cascade that occurs so that we have gene expression changes, so that we see increases in the lifespan in animals, so that we see decreases in cancer incidents and neurodegeneration and many other long-term diseases in animal models. Now, will we see these in human beings? I don’t know. The calorie study that was a clinical trial looking at calorie restriction in people, some of the things we did see was a decrease in fasting glucose levels. We did see a decrease in atherosclerosis. High blood pressure just drop down to where these people were teenagers again almost. Seeing how heart disease is the number one killer in America, it may extend human lifespan just by being calorie restricted, but it’s hard.
Dr. Pompa:
That’s right.
Alan:
I did it for 30 days because I study this, and my wife was so happy when I stopped.
Dr. Pompa:
Long-term caloric restriction is really impossible, I mean, without affecting other metabolic states, mechanisms in the cell, meaning that the body will think it’s starving eventually and start lowering its metabolism further and further. That’s why it doesn’t work for weight loss long term, right? When I studied all the stuff on caloric restriction, I realized, okay, this is—there’s truth here. However, they’re looking at animal studies. When we look at human populations, they don’t do it by eating half their dinner and move it aside. That doesn’t last, as you and I both found out the hard way. In humans, I find out that what does work is eat less by eating less often.
At the end of the day—when I started squishing how many times I eat a day down into a window, at the end of the day, I always eat less, but I eat to full every time I eat. Therefore, my body never thinks it’s starving, and I don’t get this metabolic thing. However, with that said, I have a lot of clients; my doctors have a lot of clients and patients that this is very difficult. Now, we use oxaloacetate as this leverage to really help them in this process of learning this style of eating, to eat less, really, and to live longer.
Alan:
Yeah, let me talk a little bit about how we found that. In going through the literature, we saw that increasing the NAD+ to NADH ratio really starts off the calorie restriction metabolic cascade. Where they were going with this in Harvard and MIT, these guys were very smart, and they were doing genetic engineering to get there. I thought that’s really clever, but it’s not something we’re going to do anytime in the near future. I started looking for compounds that could increase NAD levels while decreasing NADH and, preferably, a natural compound, so I didn’t have to go through as much hoops with the FDA. Preferably, a human compound so that toxicity would be less of an issue.
In going through the energy pathways, the molecular pathways, I found oxaloacetate, which is part of the Krebs cycle. I’m not a biologist, so I sought out some help from a very, very smart guy at UCLA. He’ll probably win a Nobel Prize at some point in time. I went into his office, and I told him what I was thinking and why I was thinking this and how it related to the NAD and NADH ratio. He just looked at me and got up, didn’t say a word, walked out of his office. I thought I had really offended him. All of a sudden, he looks back behind him and says, “Well, come on.” He took me downstairs. He opens up this door, couldn’t see anything behind it, big fire door. He pulls it open, and there’s a huge lab there. We’re in CMME in UCSD in San Diego.
He goes over to a bench, and he takes his arm, and he goes k-r-r-r-r-r. He just pushes everything aside, and he goes, “This is your spot.” I’m like, “What are you talking about?” He goes, “Oh, well, we’ll just get some oxaloacetate. We’ll get some fruit flies, and we’ll see if they longer. Let’s try it.” I said, “You know I’m not a biologist.” He goes, “How tough can this be? They’re either alive or they’re dead.”
We ended up actually getting worms, little C. elegans worms because they’re a little bit simpler on the evolutionary scale. We tested it, and the first time we tried it we saw an increase in lifespan of 35%. I started to cry. My wife thought I had lost my mind. I’m crying over worms, but it was very interesting. We then started ordering special worms that had part of their genes deactivated so that we could follow along the molecular pathway of how all this was working, how it was turning on metabolism, how it was turning on genes, how it was interacting environment with the genes. What we saw is the increase in the NAD to NADH ratio activates something called AMPK, which is the same thing that Metformin does, which is a diabetic drug.
Dr. Pompa:
Basically, that stimulates a pathway called autophagy, which, basically, your body gets rid of bad cells, and then it stimulates a new stem cell to replace the bad cells, pretty magical.
Alan:
Yeah, and we’ve done some work. A lot of work has been done at the University of Kansas in preclinical work to some diseases that we’re looking at. One of the things we saw is it increases mitochondrial biogenesis so the mitochondria, the little power plants of your cell. Giving oxaloacetate and turning on this calorie restriction metabolic cascade not only gets rid of the old cells, the autophagy that we’re talking about…
Dr. Pompa:
It upregulates the new mitochondria.
Alan:
Yeah, so we’re getting higher mitochondrial densities in the brain. I don’t know about you, but I can always use higher mitochondria densities in the brain because that just helps with the energy to do what the cells need to do.
Dr. Pompa:
I mean, when we look at people who are challenged, they’re sick. They’re not functioning well at the cellular level. Brain fog, it’s the top five symptoms that people have, and we know it’s a drop of brain energy, cellular energy in the brain, glucose or ketones. There’s something affected metabolically, so upregulating that, one of the things that I noticed using oxaloacetate with these people is, hey, it helps my brain fog.
Alan:
I hear that a lot from people. They say I’m now aware. I’m like it sounds a little mystical to me, but okay, I’m glad you’re aware.
Dr. Pompa:
Yeah, so I mean, this pathway you’re describing, people watching and listening to this show have heard me talk a lot about fasting. Just to pull them back into this conversation a little bit, I’ve talked about how fasting upregulates through this AMPK pathway, autophagy. Then the body will utilize these bad cells, but it doesn’t stop there. It stimulates a stem cell and replaces new, and that happens with cells. It happens with the mitochondria that we’re—we make energy, the powerhouses in the cells. Your body’s creating new ones, to your point, and we see this happen.
In this ratio, folks, when we fast, we see this ratio of NAD+ and NADH. We see this ratio get bigger, meaning you get more NAD+. That’s a positive thing. We just know that happens when people fast or in restricted calorie states, and so what you’re saying is that we see this when we take this oxaloacetate. We see this NADH ratio go up. We see it kick in some type of autophagy via AMPK. We see some type of biogenesis of mitochondria, which is obviously happening from stem cell creation somehow, so it’s mimicking what’s happening in a fasting state.
Alan:
Yeah, and when we looked at the gene expression, we did this in mice. You have to pick which pieces of the mouse that you look at, and we looked at liver function. One of the things we saw is there was almost 100% correlation between the genes that we were upregulating and downregulating compared to calorie restriction. I mean, it was pretty amazing.
Dr. Pompa:
We have the same pathways that we see in a fasting state, NADH rising— or NAD+ rising, NADH lowering. That increases the ratio. We see the AMPK pathway stimulated, which stimulates autophagy. We see, obviously, the production, the biogenesis of mitochondria, so we know there’s a stem cell direction. So far we’re mimicking this fasting state, which is the only thing that we know really is linked to living longer healthy, right? Now, you said that even this other pathway is also being stimulated as well, which mimics fasting.
Alan:
Yeah, interestingly, when we take animals and damage their liver and then feed them oxaloacetate, we’re able to turn on the biogenesis of their liver tissue and allow them to heal faster in the liver.
Dr. Pompa:
Are those some of the clinical trials you’re actually doing?
Alan:
Some of the clinical trials we’re actually doing, we just finished a Phase II trial in Alzheimer’s disease. One of the things we’re seeing in the animal models is we’re increasing glucose uptake into the brain, which a lot of people refer to Alzheimer’s as stage 3 diabetes instead of stage1, stage 2, stage 3. That’s because in Alzheimer’s patients, in the hippocampus, an area where we generate new cells that help us with retained memories and things like that, you see a drop off of glucose uptake into the cells. It’s like the glucose is there, but they can’t pull it up into their cells. Oxaloacetate’s been able to help that in animal models. We just finished a Phase II trial, and the interim data I can talk about. The full data has not been published yet, so I can’t talk about that. The interim data showed an increase in glucose uptake into the hippocampus and an increase in glutathione levels in the brain so very, very exciting information and very hopeful information. We’ll see how that develops further.
Dr. Pompa:
That makes sense on how it works in the brain. I’ve seen it help these people as well clinically. How does it affect the liver like that when you say help regenerate the liver cells?
Alan:
There are a couple of things. I mean, first it turns on the calorie restriction metabolic cascade, which increase PGC-1 alpha, which turns on mitochondrial biogenesis. It turns on DNA synthesis, and interestingly, we were a little bit concerned by that. What if it just continues to do that? That doesn’t sound good. When the cells get to a certain density, they stop. They turn off. It’s just like a faster repair kit, which is really neat.
Dr. Pompa:
Yeah, it’s interesting.
Alan:
In liver management, there have been a couple of papers now showing that oxaloacetate protects the liver from a variety of environmental toxins, like chlorinated pesticides, hydrogen peroxide. A lot of free radical damage can be ameliorated with oxaloacetate, so that’s very exciting too.
Dr. Pompa:
Some of the methods are—we talked about neurodegenerative conditions. I mean, anything from Alzheimer’s you already mentioned, obviously dementia. What about Parkinson’s and some of these other neurodegenerative conditions?
Alan:
I sell a nutritional supplement, and the supplement is not intended to prevent, treat, cure any disease.
Dr. Pompa:
I’m asking if they’re doing any trials on that, so I’m not asking you that. I’m asking the more safe question. Are they doing any clinical trials with those conditions?
Alan:
Yes, they are. Some of the interesting things, one of the other functions of oxaloacetate that is very unusual is that it can lower glutamate levels in the brain, and we see that. It’s called glutamate scavenging. It happens because the oxaloacetate goes through the lower circulatory system, and as it does that, if there is excess glutamate in the presence of a liver enzyme that’s pretty much always available—it’s called SGOT, or now it’s called AST. It binds up that oxaloacetate and makes alpha ketoglutarate, and in doing that, it can lower excess glutamate levels by 60% in the lower circulatory system and 40% in the brain. That turns out to be a really big deal.
To give you an example, I was walking through the park in Barcelona. My middle daughter is a volleyball player, professional volleyball player, and I was waiting for a game to start and just walking through the park looking at the architecture. I trip over a sprinkler head. I go flying forward, and so I try to run out of my trip.
Dr. Pompa:
We’ve all done that, embarrassingly.
Alan:
Instead of just falling down going, oh, aren’t I stupid, I instead accelerate to top speed and then stopped by a granite wall, by ramming my head into a granite wall. My wife comes around the corner. She sees this big group of people standing around this guy who’s lying on the ground in a pool of blood. They called the ambulance. They didn’t know how to get me out of there because this was not at street level. It was one floor down and in a sunken pit. I’m a big guy, and these Spanish people were not as large as I am. I was just rolling on the ground.
My wife took to two benaGene lozenges and just stuck them under my tongue, and in one minute—I had been going into shock. Came out of it like that. I sat up. I said, “Okay, here’s what we’re going to do,” and I directed my evacuation to the hospital. Bringing down glutamate levels quickly can be very advantageous in certain circumstances, and unfortunately, I had to experience that. In animal models, when we do closed head injury tests, you can reduce ischemia by 80% if you get oxaloacetate to them within two hours.
Dr. Pompa:
Wow! Somehow your wife knew that. I mean, obviously, you must educate her about this.
Alan:
We have daughters in sports, and so we always have a bag of [00:27:19].
Dr. Pompa:
benaGene, by the way, is the product that Revelation Health carries that contains oxaloacetate for those watching.
Alan:
Yeah, it’s a little pill. Each capsule is 100 mg of oxaloacetate and 150 mg of Vitamin C. The Vitamin C helps to stabilize the oxaloacetate. Oxaloacetate wasn’t available until relatively recently. It is such an energetic molecule that it would break down spontaneously in a couple of weeks at room temperature into pyruvate and carbon dioxide, neither of which are all that bad, but they’re not oxaloacetate. We had to figure out how to stabilize this and keep it. We can now keep it for up to two years at room temperature. It’s just a product that we can get out to the public to help them.
Dr. Pompa:
No, it’s a tremendous discovery. I don’t know if Ashley—Ashley, we’ll put a link to the product that we utilize with oxaloacetate in it, benaGene, below. Revelation Heath will have a special on it. I don’t know. I should’ve checked coming into the show, but I’m sure they will because now that I mentioned it. No, I love the product. I think it was an amazing discovery, stabilizing the—and everybody should be using it. I mean, I could just tell you clinically. I can only speak clinically. We’ve had great success with diabetics. We’ve had great success with athletes; they love it.
Obviously, we talked about some of the neurodegenerative conditions. I know my docs use it for autism patients with great success as well. Head trauma, I think you mentioned. I may be leaving some on the plate there, but you can see, if it has to do with metabolism of the energy and glucose and fats and all that, it works. It works very well.
Alan:
Yeah, it’s amazing how many things relate back to that. I mean, that’s basic.
Dr. Pompa:
Yeah, no, that’s why I think it’s an important player as far as—it does. It works into that pathway into the cell that so many people have broken now. They’re having trouble utilizing glucose in the cell. They’re having trouble with mitochondrial function. They’re having trouble getting glucose into the brain, being utilized. I mean, the list goes on.
Alan:
Yeah, it’s interesting. We’re still finding new uses for oxaloacetate, and a lot of what we do comes from the field where our doctors will come to us. In one case, we had a series of doctors come to us and say you know what? I’ve had some women. I’ve given this to them because they were a little—their glucose was a little bit off, so I thought this might help them. They came back, and they said, doc, my PMS didn’t come this week or this month. They were like, oh, fine, just like I would be. Oh, okay, good, that’s good. No, you don’t understand!
Some of these women have had serious problems, and some of them just have mild irritation or a little bit of mild feeling gloomy or anxiety. This seemed to reduce that considerably, and I kept hearing this again and again and again. I was like hmmm. I have three daughters, so I know the importance of this and just everything, dealing with your boyfriend, dealing with your wife, dealing with your children, dealing with your coworkers. I mean, it’s so important to be able to have a smooth ride emotionally. We decide to try it clinically. We ended up doing two clinical trials. We measured for anxiety, for gloomy mood, for perceived stress, and for irritation. What we saw is we were able to reduce those levels, especially anxiety and gloomy mood by over 50% in these women. I mean, it was life changing for them, life changing.
I mean, it’s funny. During the trial, we’d get these long emails, oh, my symptoms and, oh, my boyfriend, and, oh I’m going to lose my job. Then a couple of months later, they’d say, okay, well, things are a lot better, and the emails would be one-third the size. Then a couple of months after that, they’d just be one line. Send more. That’s what it should be. I mean, it shouldn’t be that their whole life revolves around their emotional state during that time of the month. They should be able to just blow through that and be themselves all the time.
After the clinical trials came out, we thought we should have the same product, except it should be for women, so we renamed it Jubilance. We have both benaGene on the market and Jubilance on the market for women. We are just getting a lot of thank you notes.
Dr. Pompa:
Yeah, no, exactly. Gosh, I hope we carry the Jubilance. I think Revelation Health does. Anyways, yeah, that’s fantastic. I know, my doctors, they utilize this product as well, and we see similar results. What’s the dosing? I mean, if someone’s watching this, I don’t want to have to answer a zillion emails. Where should they start? Is it different? Do you need higher doses with, say, dementia, Alzheimer’s people versus say [00:33:38]?
Alan:
As a nutritional supplement, I can’t really go into that. I mean, I know, in the Alzheimer’s trials, we’re looking at very high dosage.
Dr. Pompa:
Just speak what is being used in the trial.
Alan:
Again, that’s not what benaGene or Jubilance is looking to do. benaGene is around 100 mg. We’re treating in these trials at 2,000 mg, so it’d be the equivalent of 20 capsules a day, which is quite a bit, but if you’ve got a serious neurological condition, you may be willing to do something like that. It’s interesting with the emotional PMS, and we’ve tracked that down to it seems to be a lack of glucose in the cerebellum, in the back of the brain. If we give women who have emotional issues during that time PET scans and look at normal controls, you see a statistical difference whereas the women who have these emotional issues have huge glucose utilization. This is probably also why they’re reaching for chocolate bars, or ice cream, or other carbohydrates to try to get that glucose into their brain. They’re angry.
Dr. Pompa:
What’s funny is I have a principle, my diet variation principle, and the monthly principle, we up the carbohydrates the week before their period, healthy carbohydrates. We know that hormone convergence are actually needed, so women do need for multiple reasons. You’re giving us even another one why women will crave carbohydrates around their period. Especially, we have a lot of women who are on very low-carb diets, and they seem to mess up their whole month hormonally unless they run the healthy higher carbs the week before their period. It’s hormonal and brain.
Alan:
Yeah, so what the oxaloacetate appears to be doing is, in the liver, it’s the first step in a process called gluconeogenesis where your body will take your fats, your fatty acids, your triglycerides, and turn them into energy so that you can utilize it in your brain. If you don’t have enough oxaloacetate, you’re going to be deficit in that, so just a small amount seems to be very effective in these women.
Dr. Pompa:
Yeah, I mean, typically, we’re dosing, I mean, 300 mg, 100 to 300 mg. I mean, we see a positive result, but maybe a good strategy too is dosing high during that time for women, I mean, dosing a little a higher that week before.
Alan:
They seem to be okay at 100 to 200, 1 to 2 capsules a day. I mean, we asked [00:36:55]. I mean, the p-values which look at how certain your statistics look, how sure you are of your answer, I mean, the p-values were 10 to the minus 5. I mean, it was just phenomenal the response that we had with this. Now, with other conditions, you may want to increase the oxaloacetate higher if you’re trying to do something for someone’s neurology. Maybe trying to do some liver repair or trying to do some detoxification. Oxaloacetate works amazingly well to take on these environmental toxins like chlorinated pesticides.
Dr. Pompa:
Yeah, when you said that, interesting.
Alan:
For the most of us, one capsule a day is just great, and that’s initially what we looked at it for was anti-aging. I mean, we recently came out with one capsule a day was because a clinical trial that was done in Japan. Way back in 1968, they were looking at diabetics. One of the things we’d see with calorie restriction or fasting is it virtually eliminates type II diabetes, at least in primates, in animal models, and in giving them oxaloacetate, they were seeing the same thing. They were seeing reductions in fasting glucose levels, and now we know pretty much why. It’s because we’re turning on that AMPK pathway, very similar to what some other compounds do. That’s not our real focus, but that was our test to see are we getting that molecular cascade to have calorie restrictions? Maybe see an increase in our ability to stay younger for longer, stay healthier for longer, and so that’s why we developed this product and got it out onto the market.
Dr. Pompa:
We appreciate you doing that, honestly, and I’m so glad I finally got you on the show. There’s a lot of people now who are going to know about something that I’ve been looking at for some years now and even put this pathway in the book. I mentioned oxaloacetate so yeah.
Alan:
Thank you.
Dr. Pompa:
Absolutely, well, great stuff, Alan. Thank you for what you’re doing and your contribution to this area. It’s been a big one.
Alan:
Oh, and vice versa, I think your work on the fasting is extremely important. Between doing periodic fasting and some of these calorie restrictions, the [00:39:55] that people like myself are researching, I think we’re really going to help a lot of people.
Dr. Pompa:
There is no doubt. This is the real science here. This is the real deal. It really is. I say that because there’s so many gimmicks out there, and you wouldn’t be on the show if this was one of them. Obviously, this is a real deal, and there are studies to prove it. Thank you, Alan. Appreciate you.
Alan:
Thank you, and appreciate you giving me the opportunity to share some of our research.
Dr. Pompa:
Absolutely, and folks, we’ll put the links below for the benaGene and also the other product that he mentions. Thank you, Alan.
Alan:
Take care.
Ashley:
That’s it for this week. We hope you enjoyed today’s episode. This episode was brought to you by CytoDetox. Please check it out at buycytonow.com. We’ll be back next week and every Friday at 10 a.m. Eastern. We truly appreciate your support. You can always find us at cellularhealing.tv. Please remember to spread the love by liking, subscribing, giving an iTunes review, and sharing the show with anyone you think may benefit from the information heard here, and as always, thanks for listening.
